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Elucidation of Final Steps of the Marineosins Biosynthetic Pathway through Identification and Characterization of the Corresponding Gene Cluster

[Image: see text] The marine Streptomyces sp. CNQ-617 produces two diastereomers, marineosins A and B. These are structurally related to alkyl prodiginines, but with a more complex cyclization and an unusual spiroaminal skeleton. We report the identification of the mar biosynthetic gene cluster and...

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Detalles Bibliográficos
Autores principales: Salem, Shaimaa M., Kancharla, Papireddy, Florova, Galina, Gupta, Shweta, Lu, Wanli, Reynolds, Kevin A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3985843/
https://www.ncbi.nlm.nih.gov/pubmed/24575817
http://dx.doi.org/10.1021/ja411544w