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pH-Induced Stability Switching of the Bacteriophage HK97 Maturation Pathway

[Image: see text] Many viruses undergo large-scale conformational changes during their life cycles. Blocking the transition from one stage of the life cycle to the next is an attractive strategy for the development of antiviral compounds. In this work, we have constructed an icosahedrally symmetric,...

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Detalles Bibliográficos
Autores principales: May, Eric R., Arora, Karunesh, Brooks, Charles L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3985869/
https://www.ncbi.nlm.nih.gov/pubmed/24495192
http://dx.doi.org/10.1021/ja410860n