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A Protective Antigen Mutation Increases the pH Threshold of Anthrax Toxin Receptor 2-Mediated Pore Formation
[Image: see text] Anthrax toxin protective antigen (PA) binds cellular receptors and self-assembles into oligomeric prepores. A prepore converts to a protein translocating pore after it has been transported to an endosome where the low pH triggers formation of a membrane-spanning β-barrel channel. F...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American
Chemical Society
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3985898/ https://www.ncbi.nlm.nih.gov/pubmed/24641616 http://dx.doi.org/10.1021/bi5000756 |