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A Half-Zippered SNARE Complex Represents a Functional Intermediate in Membrane Fusion

[Image: see text] SNARE (soluble N-ethylmaleimide-sensitive factor attachment protein receptor) proteins mediate fusion by pulling biological membranes together via a zippering mechanism. Recent biophysical studies have shown that t- and v-SNAREs can assemble in multiple stages from the N-termini to...

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Detalles Bibliográficos
Autores principales: Li, Feng, Kümmel, Daniel, Coleman, Jeff, Reinisch, Karin M., Rothman, James E., Pincet, Frederic
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3985920/
https://www.ncbi.nlm.nih.gov/pubmed/24533674
http://dx.doi.org/10.1021/ja410690m