Dynamic Determination of Active-Site Reactivity in Semiquinone Photolyase by the Cofactor Photoreduction

[Image: see text] Photolyase contains a flavin cofactor in a fully reduced form as its functional state to repair ultraviolet-damaged DNA upon blue light absorption. However, after purification, the cofactor exists in its oxidized or neutral semiquinone state. Such oxidization eliminates the repair...

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Detalles Bibliográficos
Autores principales: Liu, Zheyun, Tan, Chuang, Guo, Xunmin, Li, Jiang, Wang, Lijuan, Zhong, Dongping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3985926/
https://www.ncbi.nlm.nih.gov/pubmed/24803991
http://dx.doi.org/10.1021/jz500077s

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3985926/
https://www.ncbi.nlm.nih.gov/pubmed/24803991
http://dx.doi.org/10.1021/jz500077s

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