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Coordinating Role of His216 in MgATP Binding and Cleavage in Pyruvate Carboxylase

[Image: see text] His216 is a well-conserved residue in pyruvate carboxylases and, on the basis of structures of the enzyme, appears to have a role in the binding of MgATP, forming an interaction with the 3′-hydroxyl group of the ribose ring. Mutation of this residue to asparagine results in a 9-fol...

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Detalles Bibliográficos
Autores principales: Adina-Zada, Abdussalam, Jitrapakdee, Sarawut, Wallace, John C., Attwood, Paul V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3985934/
https://www.ncbi.nlm.nih.gov/pubmed/24460480
http://dx.doi.org/10.1021/bi4016814