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Coordinating Role of His216 in MgATP Binding and Cleavage in Pyruvate Carboxylase
[Image: see text] His216 is a well-conserved residue in pyruvate carboxylases and, on the basis of structures of the enzyme, appears to have a role in the binding of MgATP, forming an interaction with the 3′-hydroxyl group of the ribose ring. Mutation of this residue to asparagine results in a 9-fol...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American
Chemical Society
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3985934/ https://www.ncbi.nlm.nih.gov/pubmed/24460480 http://dx.doi.org/10.1021/bi4016814 |