Mapping Structurally Defined Guanine Oxidation Products along DNA Duplexes: Influence of Local Sequence Context and Endogenous Cytosine Methylation

[Image: see text] DNA oxidation by reactive oxygen species is nonrandom, potentially leading to accumulation of nucleobase damage and mutations at specific sites within the genome. We now present the first quantitative data for sequence-dependent formation of structurally defined oxidative nucleobas...

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Detalles Bibliográficos
Autores principales: Ming, Xun, Matter, Brock, Song, Matthew, Veliath, Elizabeth, Shanley, Ryan, Jones, Roger, Tretyakova, Natalia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3985951/
https://www.ncbi.nlm.nih.gov/pubmed/24571128
http://dx.doi.org/10.1021/ja411636j

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3985951/
https://www.ncbi.nlm.nih.gov/pubmed/24571128
http://dx.doi.org/10.1021/ja411636j

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