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Diaryl and Heteroaryl Sulfides: Synthesis via Sulfenyl Chlorides and Evaluation as Selective Anti-Breast-Cancer Agents

[Image: see text] A mild protocol for the synthesis of diaryl and heteroaryl sulfides is described. In a one-pot procedure, thiols are converted to sulfenyl chlorides and reacted with arylzinc reagents. This method tolerates functional groups including aryl fluorides and chlorides, ketones, as well...

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Detalles Bibliográficos
Autores principales: Yonova, Ivelina M., Osborne, Charlotte A., Morrissette, Naomi S., Jarvo, Elizabeth R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3985953/
https://www.ncbi.nlm.nih.gov/pubmed/24564865
http://dx.doi.org/10.1021/jo402586v