Cargando…

A Kinase-Independent Activity of Cdk9 Modulates Glucocorticoid Receptor-Mediated Gene Induction

[Image: see text] A gene induction competition assay has recently uncovered new inhibitory activities of two transcriptional cofactors, NELF-A and NELF-B, in glucocorticoid-regulated transactivation. NELF-A and -B are also components of the NELF complex, which participates in RNA polymerase II pausi...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhu, Rong, Lu, Xinping, Pradhan, Madhumita, Armstrong, Stephen P., Storchan, Geoffrey B., Chow, Carson C., Simons, S. Stoney
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3985961/
https://www.ncbi.nlm.nih.gov/pubmed/24559102
http://dx.doi.org/10.1021/bi5000178