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Global migration and the changing distribution of sickle haemoglobin: a quantitative study of temporal trends between 1960 and 2000

BACKGROUND: Changes in the geographical distribution of genetic disorders are often thought to happen slowly, especially when compared with infectious diseases. Whereas mutations, genetic drift, and natural selection take place over many generations, epidemics can spread through large populations wi...

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Detalles Bibliográficos
Autores principales: Piel, Frédéric B, Tatem, Andrew J, Huang, Zhuojie, Gupta, Sunetra, Williams, Thomas N, Weatherall, David J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3986033/
https://www.ncbi.nlm.nih.gov/pubmed/24748392
http://dx.doi.org/10.1016/S2214-109X(13)70150-5