IGF2 Ameliorates Amyloidosis, Increases Cholinergic Marker Expression and Raises BMP9 and Neurotrophin Levels in the Hippocampus of the APPswePS1dE9 Alzheimer’s Disease Model Mice

The development of an effective therapy for Alzheimer’s disease (AD) is a major challenge to biomedical sciences. Because much of early AD pathophysiology includes hippocampal abnormalities, a viable treatment strategy might be to use trophic factors that support hippocampal integrity and function....

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Detalles Bibliográficos
Autores principales: Mellott, Tiffany J., Pender, Sarah M., Burke, Rebecca M., Langley, Erika A., Blusztajn, Jan Krzysztof
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3986048/
https://www.ncbi.nlm.nih.gov/pubmed/24732467
http://dx.doi.org/10.1371/journal.pone.0094287

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3986048/
https://www.ncbi.nlm.nih.gov/pubmed/24732467
http://dx.doi.org/10.1371/journal.pone.0094287

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