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Cost-Effectiveness Analysis of HLA-B*5801 Testing in Preventing Allopurinol-Induced SJS/TEN in Thai Population

BACKGROUND: Stevens-Johnson syndrome (SJS) and Toxic Epidermal Necrolysis (TEN), caused by allopurinol therapy, are strongly associated with the human leukocyte antigen (HLA), HLA-B*5801. Identification of HLA-B*5801 genotype before prescribing allopurinol offers the possibility of avoiding allopuri...

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Detalles Bibliográficos
Autores principales: Saokaew, Surasak, Tassaneeyakul, Wichittra, Maenthaisong, Ratree, Chaiyakunapruk, Nathorn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3986079/
https://www.ncbi.nlm.nih.gov/pubmed/24732692
http://dx.doi.org/10.1371/journal.pone.0094294