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Ubiquitin Carboxyl Terminal Hydrolyase L1 -Suppressed Autophagic Degradation of p21(WAF1/Cip1) as a Novel Feedback Mechanism in the Control of Cardiac Fibroblast Proliferation

AIMS: Deubiquitinating enzymes (DUBs) appear to be critical regulators of a multitude of processes such as proliferation, apoptosis, differentiation, and inflammation; however, the potential roles of DUBs in the heart remain to be determined. This study was aimed to explore the role of a DUB, ubiqui...

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Detalles Bibliográficos
Autores principales: Zhang, Xiaoming, Guo, Linlin, Niu, Ting, Shao, Lei, Li, Huanjie, Wu, Weiwei, Wang, Wenjuan, Lv, Linmao, Qin, Qingyun, Wang, Fang, Tang, Dongqi, Wang, Xing Li, Cui, Taixing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3986084/
https://www.ncbi.nlm.nih.gov/pubmed/24732420
http://dx.doi.org/10.1371/journal.pone.0094658