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Adventitial Delivery of Lentivirus-shRNA-ADAMTS-1 Reduces Venous Stenosis Formation in Arteriovenous Fistula

Hemodialysis vascular access can develop venous neointimal hyperplasia (VNH) causing stenosis. Recent clinical and experimental data has demonstrated that there is increased expression of a disintegrin and metalloproteinase thrombospondin motifs-1 (ADAMTS-1) at site of VNH. The experiments outlined...

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Detalles Bibliográficos
Autores principales: Nieves Torres, Evelyn C., Yang, Binxia, Janardhanan, Rajiv, Brahmbhatt, Akshaar, Leof, Ed, Mukhopadhyay, Debabrata, Misra, Sanjay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3986087/
https://www.ncbi.nlm.nih.gov/pubmed/24732590
http://dx.doi.org/10.1371/journal.pone.0094510