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Attenuation of Pathogenic Immune Responses during Infection with Human and Simian Immunodeficiency Virus (HIV/SIV) by the Tetracycline Derivative Minocycline

HIV immune pathogenesis is postulated to involve two major mechanisms: 1) chronic innate immune responses that drive T cell activation and apoptosis and 2) induction of immune regulators that suppress T cell function and proliferation. Both arms are elevated chronically in lymphoid tissues of non-na...

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Detalles Bibliográficos
Autores principales: Drewes, Julia L., Szeto, Gregory L., Engle, Elizabeth L., Liao, Zhaohao, Shearer, Gene M., Zink, M. Christine, Graham, David R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3986096/
https://www.ncbi.nlm.nih.gov/pubmed/24732038
http://dx.doi.org/10.1371/journal.pone.0094375