Cargando…

Attenuation of Pathogenic Immune Responses during Infection with Human and Simian Immunodeficiency Virus (HIV/SIV) by the Tetracycline Derivative Minocycline

HIV immune pathogenesis is postulated to involve two major mechanisms: 1) chronic innate immune responses that drive T cell activation and apoptosis and 2) induction of immune regulators that suppress T cell function and proliferation. Both arms are elevated chronically in lymphoid tissues of non-na...

Descripción completa

Detalles Bibliográficos
Autores principales:	Drewes, Julia L., Szeto, Gregory L., Engle, Elizabeth L., Liao, Zhaohao, Shearer, Gene M., Zink, M. Christine, Graham, David R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3986096/ https://www.ncbi.nlm.nih.gov/pubmed/24732038 http://dx.doi.org/10.1371/journal.pone.0094375

Ejemplares similares

Distinct Patterns of Tryptophan Maintenance in Tissues during Kynurenine Pathway Activation in Simian Immunodeficiency Virus-Infected Macaques
por: Drewes, Julia L., et al.
Publicado: (2016)

Antiretroviral activity of the aminothiol WR1065 against Human Immunodeficiency virus (HIV-1) in vitro and Simian Immunodeficiency virus (SIV) ex vivo
por: Poirier, Miriam C, et al.
Publicado: (2009)

Mapping the Small RNA Content of Simian Immunodeficiency Virions (SIV)
por: Brameier, Markus, et al.
Publicado: (2013)

High Rate of Simian Immunodeficiency Virus (SIV) Infections in Wild Chimpanzees in Northeastern Gabon
por: Boué, Vanina, et al.
Publicado: (2015)

Host Immunity to Mycobacterium tuberculosis Infection Is Similar in Simian Immunodeficiency Virus (SIV)-Infected, Antiretroviral Therapy-Treated and SIV-Naïve Juvenile Macaques
por: Larson, Erica C., et al.
Publicado: (2023)

Neuroprotective maraviroc monotherapy in simian immunodeficiency virus-infected macaques: reduced replicating and latent SIV in the brain
por: Kelly, Kathleen M., et al.
Publicado: (2013)

Role of complement and antibodies in controlling infection with pathogenic simian immunodeficiency virus (SIV) in macaques vaccinated with replication-deficient viral vectors
por: Falkensammer, Barbara, et al.
Publicado: (2009)

Hippocampal Neuronal Loss in Infant Macaques Orally Infected with Virulent Simian Immunodeficiency Virus (SIV)
por: Carryl, Heather, et al.
Publicado: (2017)

Simian Immunodeficiency Virus (SIV)-Specific Chimeric Antigen Receptor-T Cells Engineered to Target B Cell Follicles and Suppress SIV Replication
por: Haran, Kumudhini Preethi, et al.
Publicado: (2018)

Increased cellular immune responses and CD4+ T-cell proliferation correlate with reduced plasma viral load in SIV challenged recombinant simian varicella virus - simian immunodeficiency virus (rSVV-SIV) vaccinated rhesus macaques
por: Pahar, Bapi, et al.
Publicado: (2012)

Live attenuated simian immunodeficiency virus vaccination confers superinfection resistance against macrophage-tropic and neurovirulent wild-type SIV challenge
por: Berry, Neil, et al.
Publicado: (2015)

Development and optimization of a simian immunodeficiency virus (SIV) droplet digital PCR (ddPCR) assay
por: Long, Samuel, et al.
Publicado: (2020)

Reduced neuronal population in the dorsolateral prefrontal cortex in infant macaques infected with simian immunodeficiency virus (SIV)
por: Haddad, Alexandra, et al.
Publicado: (2021)

Vaccination of Macaques with DNA Followed by Adenoviral Vectors Encoding Simian Immunodeficiency Virus (SIV) Gag Alone Delays Infection by Repeated Mucosal Challenge with SIV
por: Almond, Neil, et al.
Publicado: (2019)

Epitope specificity appears to be an important determinant of in vivo killing ability of simian immunodeficiency virus (SIV)-specific CD8+ T Cells
por: Pozzi, L, et al.
Publicado: (2012)

RNA landscapes of brain tissue and brain tissue-derived extracellular vesicles in simian immunodeficiency virus (SIV) infection and SIV-related central nervous system pathology
por: Huang, Yiyao, et al.
Publicado: (2023)

Early Emergence and Selection of a SIV-LTR C/EBP Site Variant in SIV-Infected Macaques That Increases Virus Infectivity
por: Ravimohan, Shruthi, et al.
Publicado: (2012)

CD8 T Cells Show Protection against Highly Pathogenic Simian Immunodeficiency Virus (SIV) after Vaccination with SIV Gene-Expressing BCG Prime and Vaccinia Virus/Sendai Virus Vector Boosts
por: Kato, Seiichi, et al.
Publicado: (2021)

Correction: Early Emergence and Selection of a SIV-LTR C/EBP Site Variant in SIV-Infected Macaques That Increases Virus Infectivity
por: Ravimohan, Shruthi, et al.
Publicado: (2013)

Revisiting a quarter of a century of simian immunodeficiency virus (SIV)-associated cardiovascular diseases at the German Primate Center
por: Mietsch, Matthias, et al.
Publicado: (2017)

Expression, purification, and functional characterization of soluble recombinant full-length simian immunodeficiency virus (SIV) Pr55(Gag)
por: Pillai, Vineeta N., et al.
Publicado: (2023)

Longitudinal characterization of circulating extracellular vesicles and small RNA during simian immunodeficiency virus infection and antiretroviral therapy
por: Huang, Yiyao, et al.
Publicado: (2023)

Recombinant Simian Varicella Virus-Simian Immunodeficiency Virus Vaccine Induces T and B Cell Functions and Provides Partial Protection against Repeated Mucosal SIV Challenges in Rhesus Macaques
por: Pahar, Bapi, et al.
Publicado: (2022)

Experimental co-transmission of Simian Immunodeficiency Virus (SIV) and the macaque homologs of the Kaposi Sarcoma-Associated Herpesvirus (KSHV) and Epstein-Barr Virus (EBV)
por: Bruce, A. Gregory, et al.
Publicado: (2018)

Brain Macrophages in Simian Immunodeficiency Virus-Infected, Antiretroviral-Suppressed Macaques: a Functional Latent Reservoir
por: Avalos, Claudia R., et al.
Publicado: (2017)

Emergence of resistance mutations in simian immunodeficiency virus (SIV)-infected rhesus macaques receiving non-suppressive antiretroviral therapy (ART)
por: Policicchio, Benjamin Bruno, et al.
Publicado: (2018)

Comparative pharmacokinetics of chlortetracycline, tetracycline, minocycline, and tigecycline in broiler chickens
por: Ziółkowski, Hubert, et al.
Publicado: (2020)

Quantitation of Productively Infected Monocytes and Macrophages of Simian Immunodeficiency Virus-Infected Macaques
por: Avalos, Claudia R., et al.
Publicado: (2016)

Experimental Oral Herpes Simplex Virus-1 (HSV-1) Co-infection in Simian Immunodeficiency Virus (SIV)-Infected Rhesus Macaques
por: Aravantinou, Meropi, et al.
Publicado: (2017)

Development of a reverse transcription droplet digital PCR (RT-ddPCR) assay for sensitive detection of simian immunodeficiency virus (SIV)
por: Long, Samuel, et al.
Publicado: (2021)

Protection against highly pathogenic SIV by BCG-SIV recombinant priming and attenuated replicating vaccinia-SIV recombinant boosting
por: Zhang, X, et al.
Publicado: (2012)

Minocycline Inhibition of Monocyte Activation Correlates with Neuronal Protection in SIV NeuroAIDS
por: Campbell, Jennifer H., et al.
Publicado: (2011)

P17-20. Lentiviral vector-based vaccine against SIV infection and simian AIDS
por: Beignon, A, et al.
Publicado: (2009)

Divergent HIV and Simian Immunodeficiency Virus Surveillance, Zaire
por: Schaefer, Amanda, et al.
Publicado: (2005)

Simian Immunodeficiency Virus Infection of Chimpanzees (Pan troglodytes) Shares Features of Both Pathogenic and Non-pathogenic Lentiviral Infections
por: Greenwood, Edward J. D., et al.
Publicado: (2015)

Central African Hunters Exposed to Simian Immunodeficiency Virus
por: Kalish, Marcia L., et al.
Publicado: (2005)

Innate Immunity in Simian Immunodeficiency Virus Infection
por: Reeves, Roger Keith, et al.
Publicado: (2014)

Damaged Intestinal Epithelial Integrity Linked to Microbial Translocation in Pathogenic Simian Immunodeficiency Virus Infections
por: Estes, Jacob D., et al.
Publicado: (2010)

Modeling the Effects of Morphine on Simian Immunodeficiency Virus Dynamics
por: Vaidya, Naveen K., et al.
Publicado: (2016)

Impact of Simian Immunodeficiency Virus Infection on Chimpanzee Population Dynamics
por: Rudicell, Rebecca S., et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_753nv5idrgc08tipvrtbb7jp8s