Plasminogen Deficiency Causes Reduced Corticospinal Axonal Plasticity and Functional Recovery after Stroke in Mice

Tissue plasminogen activator (tPA) has been implicated in neurite outgrowth and neurological recovery post stroke. tPA converts the zymogen plasminogen (Plg) into plasmin. In this study, using plasminogen knockout (Plg(-/-)) mice and their Plg-native littermates (Plg(+/+)), we investigated the role...

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Detalles Bibliográficos
Autores principales: Liu, Zhongwu, Li, Yi, Qian, Jianyong, Cui, Yisheng, Chopp, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3986098/
https://www.ncbi.nlm.nih.gov/pubmed/24732409
http://dx.doi.org/10.1371/journal.pone.0094505

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3986098/
https://www.ncbi.nlm.nih.gov/pubmed/24732409
http://dx.doi.org/10.1371/journal.pone.0094505

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