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Development of Genetically Flexible Mouse Models of Sarcoma Using RCAS-TVA Mediated Gene Delivery

Sarcomas are a heterogeneous group of mesenchymal malignancies and unfortunately there are limited functional genomics platforms to assess the molecular pathways contributing to sarcomagenesis. Thus, novel model systems are needed to validate which genes should be targeted for therapeutic interventi...

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Detalles Bibliográficos
Autores principales: Kabaroff, Leah, Gupta, Amar, Menezes, Serena, Babichev, Yael, Kandel, Rita C., Swallow, Carol J., Dickson, Brendan C., Gladdy, Rebecca A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3986235/
https://www.ncbi.nlm.nih.gov/pubmed/24733554
http://dx.doi.org/10.1371/journal.pone.0094817