Activation of AMPKα2 Is Not Crucial for Mitochondrial Uncoupling-Induced Metabolic Effects but Required to Maintain Skeletal Muscle Integrity

Transgenic (UCP1-TG) mice with ectopic expression of UCP1 in skeletal muscle (SM) show a phenotype of increased energy expenditure, improved glucose tolerance and increase substrate metabolism in SM. To investigate the potential role of skeletal muscle AMPKα2 activation in the metabolic phenotype of...

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Detalles Bibliográficos
Autores principales: Ost, Mario, Werner, Franziska, Dokas, Janine, Klaus, Susanne, Voigt, Anja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3986237/
https://www.ncbi.nlm.nih.gov/pubmed/24732703
http://dx.doi.org/10.1371/journal.pone.0094689

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3986237/
https://www.ncbi.nlm.nih.gov/pubmed/24732703
http://dx.doi.org/10.1371/journal.pone.0094689

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