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Staphylococcus aureus Alpha-Toxin Mediates General and Cell Type-Specific Changes in Metabolite Concentrations of Immortalized Human Airway Epithelial Cells

Staphylococcus aureus alpha-toxin (Hla) is a potent pore-forming cytotoxin that plays an important role in the pathogenesis of S. aureus infections, including pneumonia. The impact of Hla on the dynamics of the metabolome in eukaryotic host cells has not been investigated comprehensively. Using (1)H...

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Detalles Bibliográficos
Autores principales: Gierok, Philipp, Harms, Manuela, Richter, Erik, Hildebrandt, Jan-Peter, Lalk, Michael, Mostertz, Jörg, Hochgräfe, Falko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3986243/
https://www.ncbi.nlm.nih.gov/pubmed/24733556
http://dx.doi.org/10.1371/journal.pone.0094818