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Staphylococcus aureus Alpha-Toxin Mediates General and Cell Type-Specific Changes in Metabolite Concentrations of Immortalized Human Airway Epithelial Cells
Staphylococcus aureus alpha-toxin (Hla) is a potent pore-forming cytotoxin that plays an important role in the pathogenesis of S. aureus infections, including pneumonia. The impact of Hla on the dynamics of the metabolome in eukaryotic host cells has not been investigated comprehensively. Using (1)H...
Autores principales: | Gierok, Philipp, Harms, Manuela, Richter, Erik, Hildebrandt, Jan-Peter, Lalk, Michael, Mostertz, Jörg, Hochgräfe, Falko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3986243/ https://www.ncbi.nlm.nih.gov/pubmed/24733556 http://dx.doi.org/10.1371/journal.pone.0094818 |
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