Atrial Fibrillation-Linked Germline GJA5/Connexin40 Mutants Showed an Increased Hemichannel Function

Mutations in GJA5 encoding the gap junction protein connexin40 (Cx40) have been linked to lone atrial fibrillation. Some of these mutants result in impaired gap junction function due to either abnormal connexin localization or impaired gap junction channels, which may play a role in promoting atrial...

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Detalles Bibliográficos
Autores principales: Sun, Yiguo, Hills, Matthew D., Ye, Willy G., Tong, Xiaoling, Bai, Donglin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3986259/
https://www.ncbi.nlm.nih.gov/pubmed/24733048
http://dx.doi.org/10.1371/journal.pone.0095125

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3986259/
https://www.ncbi.nlm.nih.gov/pubmed/24733048
http://dx.doi.org/10.1371/journal.pone.0095125

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