Development of nucleic acid vaccines: use of self-amplifying RNA in lipid nanoparticles

Self-amplifying RNA or RNA replicon is a form of nucleic acid-based vaccine derived from either positive-strand or negative-strand RNA viruses. The gene sequences encoding structural proteins in these RNA viruses are replaced by mRNA encoding antigens of interest as well as by RNA polymerase for rep...

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Detalles Bibliográficos
Autores principales: Rodríguez-Gascón, Alicia, del Pozo-Rodríguez, Ana, Solinís, María Ángeles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2014
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3986288/
https://www.ncbi.nlm.nih.gov/pubmed/24748793
http://dx.doi.org/10.2147/IJN.S39810

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3986288/
https://www.ncbi.nlm.nih.gov/pubmed/24748793
http://dx.doi.org/10.2147/IJN.S39810

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