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PIK3CA mutations define favorable prognostic biomarkers in operable breast cancer: a systematic review and meta-analysis

BACKGROUND: Mutations of the p110α catalytic subunit of phosphatidylinositol 3-kinase (PIK3CA) are among the most common genetic aberrations in human breast cancer. At present, controversy exists concerning the prognostic value of the mutations. METHODS: We performed a systematic review and meta-ana...

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Detalles Bibliográficos
Autores principales: Liu, Yi-Rong, Jiang, Yi-Zhou, Zuo, Wen-Jia, Yu, Ke-Da, Shao, Zhi-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3986298/
https://www.ncbi.nlm.nih.gov/pubmed/24748804
http://dx.doi.org/10.2147/OTT.S60115