PI3K/Akt-Independent NOS/HO Activation Accounts for the Facilitatory Effect of Nicotine on Acetylcholine Renal Vasodilations: Modulation by Ovarian Hormones

We investigated the effect of chronic nicotine on cholinergically-mediated renal vasodilations in female rats and its modulation by the nitric oxide synthase (NOS)/heme oxygenase (HO) pathways. Dose-vasodilatory response curves of acetylcholine (0.01–2.43 nmol) were established in isolated phenyleph...

Descripción completa

Detalles Bibliográficos
Autores principales: Gohar, Eman Y., El-gowilly, Sahar M., El-Gowelli, Hanan M., El-Demellawy, Maha A., El-Mas, Mahmoud M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3986343/
https://www.ncbi.nlm.nih.gov/pubmed/24733557
http://dx.doi.org/10.1371/journal.pone.0095079

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3986343/
https://www.ncbi.nlm.nih.gov/pubmed/24733557
http://dx.doi.org/10.1371/journal.pone.0095079

Ejemplares similares