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Numerical and Structural Genomic Aberrations Are Reliably Detectable in Tissue Microarrays of Formalin-Fixed Paraffin-Embedded Tumor Samples by Fluorescence In-Situ Hybridization

Few data are available regarding the reliability of fluorescence in-situ hybridization (FISH), especially for chromosomal deletions, in high-throughput settings using tissue microarrays (TMAs). We performed a comprehensive FISH study for the detection of chromosomal translocations and deletions in f...

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Detalles Bibliográficos
Autores principales: Horn, Heike, Bausinger, Julia, Staiger, Annette M., Sohn, Maximilian, Schmelter, Christopher, Gruber, Kim, Kalla, Claudia, Ott, M. Michaela, Rosenwald, Andreas, Ott, German
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3986364/
https://www.ncbi.nlm.nih.gov/pubmed/24733537
http://dx.doi.org/10.1371/journal.pone.0095047