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High Glucose Induces CCL20 in Proximal Tubular Cells via Activation of the KCa3.1 Channel

BACKGROUND: Inflammation plays a key role in the development and progression of diabetic nephropathy (DN). KCa3.1, a calcium activated potassium channel protein, is associated with vascular inflammation, atherogenesis, and proliferation of endothelial cells, macrophages, and fibroblasts. We have pre...

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Detalles Bibliográficos
Autores principales: Huang, Chunling, Pollock, Carol A., Chen, Xin-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3986377/
https://www.ncbi.nlm.nih.gov/pubmed/24733189
http://dx.doi.org/10.1371/journal.pone.0095173