Expression of DNAJB12 or DNAJB14 Causes Coordinate Invasion of the Nucleus by Membranes Associated with a Novel Nuclear Pore Structure

DNAJB12 and DNAJB14 are transmembrane proteins in the endoplasmic reticulum (ER) that serve as co-chaperones for Hsc70/Hsp70 heat shock proteins. We demonstrate that over-expression of DNAJB12 or DNAJB14 causes the formation of elaborate membranous structures within cell nuclei, which we designate D...

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Detalles Bibliográficos
Autores principales: Goodwin, Edward C., Motamedi, Nasim, Lipovsky, Alex, Fernández-Busnadiego, Rubén, DiMaio, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3986390/
https://www.ncbi.nlm.nih.gov/pubmed/24732912
http://dx.doi.org/10.1371/journal.pone.0094322

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3986390/
https://www.ncbi.nlm.nih.gov/pubmed/24732912
http://dx.doi.org/10.1371/journal.pone.0094322

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