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Expression of DNAJB12 or DNAJB14 Causes Coordinate Invasion of the Nucleus by Membranes Associated with a Novel Nuclear Pore Structure
DNAJB12 and DNAJB14 are transmembrane proteins in the endoplasmic reticulum (ER) that serve as co-chaperones for Hsc70/Hsp70 heat shock proteins. We demonstrate that over-expression of DNAJB12 or DNAJB14 causes the formation of elaborate membranous structures within cell nuclei, which we designate D...
Autores principales: | Goodwin, Edward C., Motamedi, Nasim, Lipovsky, Alex, Fernández-Busnadiego, Rubén, DiMaio, Daniel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3986390/ https://www.ncbi.nlm.nih.gov/pubmed/24732912 http://dx.doi.org/10.1371/journal.pone.0094322 |
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