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Down-Regulation of FcεRI-Mediated CD63 Basophil Response during Short-Term VIT Determined Venom-Nonspecific Desensitization

BACKGROUND: We recently showed a desensitization of FcεRI-mediated basophil response after short-term VIT. Our aim was to evaluate the allergen specificity of this desensitization. METHODS: In 11 Hymenoptera-venom double positive subjects, basophil threshold sensitivity (CD-sens) to anti-FcεRI, hone...

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Detalles Bibliográficos
Autores principales: Čelesnik Smodiš, Nina, Šilar, Mira, Eržen, Renato, Rijavec, Matija, Košnik, Mitja, Korošec, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3986393/
https://www.ncbi.nlm.nih.gov/pubmed/24733549
http://dx.doi.org/10.1371/journal.pone.0094762