A Chemical Genetics Analysis of the Roles of Bypass Polymerase DinB and DNA Repair Protein AlkB in Processing N (2)-Alkylguanine Lesions In Vivo

DinB, the E. coli translesion synthesis polymerase, has been shown to bypass several N (2)-alkylguanine adducts in vitro, including N (2)-furfurylguanine, the structural analog of the DNA adduct formed by the antibacterial agent nitrofurazone. Recently, it was demonstrated that the Fe(II)- and α-ket...

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Detalles Bibliográficos
Autores principales: Shrivastav, Nidhi, Fedeles, Bogdan I., Li, Deyu, Delaney, James C., Frick, Lauren E., Foti, James J., Walker, Graham C., Essigmann, John M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3986394/
https://www.ncbi.nlm.nih.gov/pubmed/24733044
http://dx.doi.org/10.1371/journal.pone.0094716

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3986394/
https://www.ncbi.nlm.nih.gov/pubmed/24733044
http://dx.doi.org/10.1371/journal.pone.0094716

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