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A Chemical Genetics Analysis of the Roles of Bypass Polymerase DinB and DNA Repair Protein AlkB in Processing N (2)-Alkylguanine Lesions In Vivo
DinB, the E. coli translesion synthesis polymerase, has been shown to bypass several N (2)-alkylguanine adducts in vitro, including N (2)-furfurylguanine, the structural analog of the DNA adduct formed by the antibacterial agent nitrofurazone. Recently, it was demonstrated that the Fe(II)- and α-ket...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3986394/ https://www.ncbi.nlm.nih.gov/pubmed/24733044 http://dx.doi.org/10.1371/journal.pone.0094716 |