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Completely ES Cell-Derived Mice Produced by Tetraploid Complementation Using Inner Cell Mass (ICM) Deficient Blastocysts

Tetraploid complementation is often used to produce mice from embryonic stem cells (ESCs) by injection of diploid (2n) ESCs into tetraploid (4n) blastocysts (ESC-derived mice). This method has also been adapted to mouse cloning and the derivation of mice from induced pluripotent stem (iPS) cells. Ho...

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Detalles Bibliográficos
Autores principales: Wen, Duancheng, Saiz, Nestor, Rosenwaks, Zev, Hadjantonakis, Anna-Katerina, Rafii, Shahin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3986396/
https://www.ncbi.nlm.nih.gov/pubmed/24733255
http://dx.doi.org/10.1371/journal.pone.0094730