Discovery of Novel Allosteric Effectors Based on the Predicted Allosteric Sites for Escherichia coli D-3-Phosphoglycerate Dehydrogenase

D-3-phosphoglycerate dehydrogenase (PGDH) from Escherichia coli catalyzes the first critical step in serine biosynthesis, and can be allosterically inhibited by serine. In a previous study, we developed a computational method for allosteric site prediction using a coarse-grained two-state Gō Model a...

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Detalles Bibliográficos
Autores principales: Wang, Qian, Qi, Yifei, Yin, Ning, Lai, Luhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3986399/
https://www.ncbi.nlm.nih.gov/pubmed/24733054
http://dx.doi.org/10.1371/journal.pone.0094829

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3986399/
https://www.ncbi.nlm.nih.gov/pubmed/24733054
http://dx.doi.org/10.1371/journal.pone.0094829

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