A Modified Screening System for Loss-of-Function and Dominant Negative Alleles of Essential MCMV Genes

Inactivation of gene products by dominant negative mutants is a valuable tool to assign functions to yet uncharacterized proteins, to map protein-protein interactions or to dissect physiological pathways. Detailed functional and structural knowledge about the target protein would allow the construct...

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Detalles Bibliográficos
Autores principales: Pogoda, Madlen, Bosse, Jens B., Conzelmann, Karl-Klaus, Koszinowski, Ulrich H., Ruzsics, Zsolt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3986410/
https://www.ncbi.nlm.nih.gov/pubmed/24733555
http://dx.doi.org/10.1371/journal.pone.0094918

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3986410/
https://www.ncbi.nlm.nih.gov/pubmed/24733555
http://dx.doi.org/10.1371/journal.pone.0094918

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