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Gene Expression Profiling Identifies Microphthalmia-Associated Transcription Factor (MITF) and Dickkopf-1 (DKK1) as Regulators of Microenvironment-Driven Alterations in Melanoma Phenotype

BACKGROUND: The diversity of functional phenotypes observed within a tumor does not exclusively result from intratumoral genetic heterogeneity but also from the response of cancer cells to the microenvironment. We have previously demonstrated that the morphological and functional phenotypes of melan...

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Detalles Bibliográficos
Autores principales: Hartman, Mariusz L., Talar, Beata, Noman, Muhammad Zaeem, Gajos-Michniewicz, Anna, Chouaib, Salem, Czyz, Malgorzata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3986414/
https://www.ncbi.nlm.nih.gov/pubmed/24733089
http://dx.doi.org/10.1371/journal.pone.0095157