Untangling the interplay of genetic and metabolic influences on beta-cell function: Examples of potential therapeutic implications involving TCF7L2 and FFAR1()

Deteriorating beta-cell function is a common feature of type 2 diabetes. In this review, we briefly address the regulation of beta-cell function, and discuss some of the main determinants of beta-cell failure. We will focus on the role of interactions between the genetic background and metabolic env...

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Detalles Bibliográficos
Autores principales: Wagner, Robert, Staiger, Harald, Ullrich, Susanne, Stefan, Norbert, Fritsche, Andreas, Häring, Hans-Ulrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3986492/
https://www.ncbi.nlm.nih.gov/pubmed/24749055
http://dx.doi.org/10.1016/j.molmet.2014.01.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3986492/
https://www.ncbi.nlm.nih.gov/pubmed/24749055
http://dx.doi.org/10.1016/j.molmet.2014.01.001

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