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Identification of the Niche and Phenotype of the First Human Hematopoietic Stem Cells
In various vertebrate species, the dorsal aorta (Ao) is the site of specification of adult hematopoietic stem cells (HSCs). It has been observed that the upregulation of essential hematopoietic transcription factors and the formation of specific intra-aortic hematopoietic cell clusters occur predomi...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3986508/ https://www.ncbi.nlm.nih.gov/pubmed/24749070 http://dx.doi.org/10.1016/j.stemcr.2014.02.004 |