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Identification of the Niche and Phenotype of the First Human Hematopoietic Stem Cells

In various vertebrate species, the dorsal aorta (Ao) is the site of specification of adult hematopoietic stem cells (HSCs). It has been observed that the upregulation of essential hematopoietic transcription factors and the formation of specific intra-aortic hematopoietic cell clusters occur predomi...

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Detalles Bibliográficos
Autores principales: Ivanovs, Andrejs, Rybtsov, Stanislav, Anderson, Richard A., Turner, Marc L., Medvinsky, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3986508/
https://www.ncbi.nlm.nih.gov/pubmed/24749070
http://dx.doi.org/10.1016/j.stemcr.2014.02.004