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Understanding the Biology of Antigen Cross-Presentation for the Design of Vaccines Against Cancer

Antigen cross-presentation, the process in which exogenous antigens are presented on MHC class I molecules, is crucial for the generation of effector CD8(+) T cell responses. Although multiple cell types are being described to be able to cross-present antigens, in vivo this task is mainly carried ou...

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Detalles Bibliográficos
Autores principales: Fehres, Cynthia M., Unger, Wendy W. J., Garcia-Vallejo, Juan J., van Kooyk, Yvette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3986565/
https://www.ncbi.nlm.nih.gov/pubmed/24782858
http://dx.doi.org/10.3389/fimmu.2014.00149