Divisional History and Hematopoietic Stem Cell Function during Homeostasis

We investigated the homeostatic behavior of hematopoietic stem and progenitor cells (HSPCs) temporally defined according to their divisional histories using an HSPC-specific GFP label-retaining system. We show that homeostatic hematopoietic stem cells (HSCs) lose repopulating potential after limited...

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Detalles Bibliográficos
Autores principales: Qiu, Jiajing, Papatsenko, Dmitri, Niu, Xiaohong, Schaniel, Christoph, Moore, Kateri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3986626/
https://www.ncbi.nlm.nih.gov/pubmed/24749072
http://dx.doi.org/10.1016/j.stemcr.2014.01.016

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