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Divisional History and Hematopoietic Stem Cell Function during Homeostasis
We investigated the homeostatic behavior of hematopoietic stem and progenitor cells (HSPCs) temporally defined according to their divisional histories using an HSPC-specific GFP label-retaining system. We show that homeostatic hematopoietic stem cells (HSCs) lose repopulating potential after limited...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3986626/ https://www.ncbi.nlm.nih.gov/pubmed/24749072 http://dx.doi.org/10.1016/j.stemcr.2014.01.016 |