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Activation of the omega-3 fatty acid receptor GPR120 mediates anti-inflammatory actions in immortalized hypothalamic neurons

BACKGROUND: Overnutrition and the ensuing hypothalamic inflammation is a major perpetuating factor in the development of metabolic diseases, such as obesity and diabetes. Inflamed neurons of the CNS fail to properly regulate energy homeostasis leading to pathogenic changes in glucose handling, feedi...

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Detalles Bibliográficos
Autores principales: Wellhauser, Leigh, Belsham, Denise D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3986641/
https://www.ncbi.nlm.nih.gov/pubmed/24674717
http://dx.doi.org/10.1186/1742-2094-11-60