Cargando…

Detailed Analysis of the Genetic and Epigenetic Signatures of iPSC-Derived Mesodiencephalic Dopaminergic Neurons

Induced pluripotent stem cells (iPSCs) hold great promise for in vitro generation of disease-relevant cell types, such as mesodiencephalic dopaminergic (mdDA) neurons involved in Parkinson’s disease. Although iPSC-derived midbrain DA neurons have been generated, detailed genetic and epigenetic chara...

Descripción completa

Detalles Bibliográficos
Autores principales: Roessler, Reinhard, Smallwood, Sebastien A., Veenvliet, Jesse V., Pechlivanoglou, Petros, Peng, Su-Ping, Chakrabarty, Koushik, Groot-Koerkamp, Marian J.A., Pasterkamp, R. Jeroen, Wesseling, Evelyn, Kelsey, Gavin, Boddeke, Erik, Smidt, Marten P., Copray, Sjef
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3986662/
https://www.ncbi.nlm.nih.gov/pubmed/24749075
http://dx.doi.org/10.1016/j.stemcr.2014.03.001