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DNA methylation subgroups and the CpG island methylator phenotype in gastric cancer: a comprehensive profiling approach

BACKGROUND: Methylation-induced silencing of promoter CpG islands in tumor suppressor genes plays an important role in human carcinogenesis. In colorectal cancer, the CpG island methylator phenotype (CIMP) is defined as widespread and elevated levels of DNA methylation and CIMP+ tumors have distinct...

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Detalles Bibliográficos
Autores principales: Loh, Marie, Liem, Natalia, Vaithilingam, Aparna, Lim, Pei Li, Sapari, Nur Sabrina, Elahi, Eiram, Mok, Zuan Yu, Cheng, Chee Leong, Yan, Benedict, Pang, Brendan, Salto-Tellez, Manuel, Yong, Wei Peng, Iacopetta, Barry, Soong, Richie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3986689/
https://www.ncbi.nlm.nih.gov/pubmed/24674026
http://dx.doi.org/10.1186/1471-230X-14-55