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Automatic Supported Liquid Extraction (SLE) Coupled with HILIC-MS/MS: An Application to Method Development and Validation of Erlotinib in Human Plasma

A novel bioanalytical method was developed and validated for the quantitative determination of erlotinib in human plasma by using the supported liquid extraction (SLE) sample cleanup coupled with hydrophilic interaction liquid chromatography and tandem mass spectrometric detection (HILIC-MS/MS). The...

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Detalles Bibliográficos
Autores principales: Pan, Jiongwei, Jiang, Xiangyu, Chen, Yu-Luan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3986710/
https://www.ncbi.nlm.nih.gov/pubmed/27721346
http://dx.doi.org/10.3390/pharmaceutics2020105