Strategies for Developing Sensitive and Automated LC-MS/MS Assays of a Pharmaceutical Compound and Its Metabolite from Whole Blood Matrix

When compared with biological samples in other matrices (plasma, urine, etc.) that are typically seen in bioanalytical applications, whole blood samples present unique challenges in method development, because of the viscous nature of blood and complexity of its constituents. In this article, we hav...

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Detalles Bibliográficos
Autores principales: Xu, Raymond N., Polzin, Jill, Kranz, Michelle, Vaca, Phillip, Metchkarova, Maria, Rieser, Matthew J., El-Shourbagy, Tawakol A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3986713/
https://www.ncbi.nlm.nih.gov/pubmed/27721348
http://dx.doi.org/10.3390/pharmaceutics2020159

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3986713/
https://www.ncbi.nlm.nih.gov/pubmed/27721348
http://dx.doi.org/10.3390/pharmaceutics2020159

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