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Asymmetric Membrane Capsules for Extended Delivery of the Weakly Basic Drug Carvedilol
The objective of this study was to demonstrate that asymmetric membrane capsules can be used to deliver a poorly water soluble drug with a pH dependent solubility, such as carvedilol, for extended periods of time by modulating solubility with acid. In this study, the effect of the concentration of p...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3986716/ https://www.ncbi.nlm.nih.gov/pubmed/27721351 http://dx.doi.org/10.3390/pharmaceutics2020199 |