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Induction of Drug Transporters Alters Disposition of Risperidone - A Study in Mice

Pharmacokinetic interactions, e.g. modulation of drug transporters like P-glycoprotein at the blood-brain barrier, can be a reason for treatment non-response. This study focuses on the influence of induction of drug transporters on the disposition of the antipsychotic drugs risperidone and 9-hydroxy...

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Detalles Bibliográficos
Autores principales: Holthoewer, David, Hiemke, Christoph, Schmitt, Ulrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3986720/
https://www.ncbi.nlm.nih.gov/pubmed/27721355
http://dx.doi.org/10.3390/pharmaceutics2020258