Ganglioside deficiency causes inflammation and neurodegeneration via the activation of complement system in the spinal cord

BACKGROUND: Gangliosides, sialic acid-containing glycosphingolipids, are highly expressed in nervous systems of vertebrates and have been considered to be involved in the development, differentiation, and function of nervous tissues. Recent studies with gene-engineered animals have revealed that the...

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Detalles Bibliográficos
Autores principales: Ohmi, Yuhsuke, Ohkawa, Yuki, Tajima, Orie, Sugiura, Yasuo, Furukawa, Keiko, Furukawa, Koichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3986855/
https://www.ncbi.nlm.nih.gov/pubmed/24673754
http://dx.doi.org/10.1186/1742-2094-11-61

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3986855/
https://www.ncbi.nlm.nih.gov/pubmed/24673754
http://dx.doi.org/10.1186/1742-2094-11-61

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